paramlink2: Parametric Linkage Analysis
Parametric linkage analysis of monogenic traits in medical pedigrees. Features include singlepoint analysis, multipoint analysis via 'MERLIN' (Abecasis et al. (2002) <doi:10.1038/ng786>), visualisation of log of the odds (LOD) scores and summaries of linkage peaks. Disease models may be specified to accommodate phenocopies, reduced penetrance and liability classes. 'paramlink2' is part of the 'pedsuite' package ecosystem, presented in 'Pedigree Analysis in R' (Vigeland, 2021, ISBN:9780128244302).
| Version: | 1.0.6 |
| Depends: | R (≥ 4.1), pedtools |
| Imports: | pedprobr |
| Suggests: | spelling, testthat |
| Published: | 2024-09-07 |
| DOI: | 10.32614/CRAN.package.paramlink2 |
| Author: | Magnus Dehli Vigeland
 [aut, cre] |
| Maintainer: | Magnus Dehli Vigeland <m.d.vigeland at medisin.uio.no> |
| BugReports: | https://github.com/magnusdv/paramlink2/issues |
| License: | GPL-3 |
| URL: | https://github.com/magnusdv/paramlink2 |
| NeedsCompilation: | no |
| SystemRequirements: | MERLIN (https://csg.sph.umich.edu/abecasis/merlin/) for multipoint linkage analysis. |
| Language: | en-GB |
| Materials: | README, NEWS |
| CRAN checks: | paramlink2 results |
Documentation:
| Reference manual: | paramlink2.html , paramlink2.pdf |
Downloads:
| Package source: | paramlink2_1.0.6.tar.gz |
| Windows binaries: | r-devel: paramlink2_1.0.6.zip, r-release: paramlink2_1.0.6.zip, r-oldrel: paramlink2_1.0.6.zip |
| macOS binaries: | r-release (arm64): paramlink2_1.0.6.tgz, r-oldrel (arm64): paramlink2_1.0.6.tgz, r-release (x86_64): paramlink2_1.0.6.tgz, r-oldrel (x86_64): paramlink2_1.0.6.tgz |
| Old sources: | paramlink2 archive |
Reverse dependencies:
| Reverse imports: | pedsuite |
Linking:
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