dinamic: A Method to Analyze Recurrent DNA Copy Number Aberrations in
Tumors
In tumor tissue, underlying genomic instability can lead to DNA copy number alterations,
e.g., copy number gains or losses. Sporadic copy number alterations occur randomly throughout the
genome, whereas recurrent alterations are observed in the same genomic region across multiple
independent samples, perhaps because they provide a selective growth advantage.
This package implements the DiNAMIC procedure for assessing the statistical significance of
recurrent DNA copy number aberrations (Bioinformatics (2011) 27(5) 678 - 685).
| Version: |
1.0.1 |
| Depends: |
R (≥ 4.2.0) |
| Suggests: |
R.rsp |
| Published: |
2024-03-15 |
| DOI: |
10.32614/CRAN.package.dinamic |
| Author: |
Vonn Walter  [aut,
cre],
Andrew B. Nobel [aut],
Fred A. Wright [aut] |
| Maintainer: |
Vonn Walter <vwalter1 at pennstatehealth.psu.edu> |
| License: |
GPL-3 |
| NeedsCompilation: |
no |
| Materials: |
README, NEWS |
| CRAN checks: |
dinamic results |
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