High-Performance Open-Source Archive
SATS stands for Signature Analyzer for Targeted Sequencing and performs mutational signature analysis for targeted sequenced tumors. Unlike the canonical analysis of mutational signatures, SATS factorizes the mutation counts matrix into a panel context matrix (measuring the size of the targeted sequenced genome for each tumor in the unit of million base pairs (Mb)), a signature profile matrix, and a signature activity matrix. SATS also calculates the expected number of mutations attributed by a signature, namely signature burden, for each targeted sequenced tumor. For more details see Lee et al. (2024) <doi:10.1101/2023.05.18.23290188>.
| Version: | 1.0.10 |
| Depends: | R (≥ 4.1.0) |
| Imports: | stats, glmnet, GenomicRanges, IRanges, Biostrings, dplyr |
| Suggests: | testthat, BSgenome.Hsapiens.UCSC.hg19, BSgenome.Hsapiens.UCSC.hg38 |
| Published: | 2026-07-09 |
| DOI: | 10.32614/CRAN.package.SATS |
| Author: | DongHyuk Lee [aut], Bin Zhu [aut], Bill Wheeler [cre] |
| Maintainer: | Bill Wheeler <wheelerb at imsweb.com> |
| License: | GPL-2 |
| NeedsCompilation: | yes |
| CRAN checks: | SATS results |
| Reference manual: | SATS.html , SATS.pdf |
| Package source: | SATS_1.0.10.tar.gz |
| Windows binaries: | r-devel: SATS_1.0.10.zip, r-release: SATS_1.0.10.zip, r-oldrel: SATS_1.0.10.zip |
| macOS binaries: | r-release (arm64): SATS_1.0.10.tgz, r-oldrel (arm64): not available, r-release (x86_64): SATS_1.0.10.tgz, r-oldrel (x86_64): not available |
| Old sources: | SATS archive |
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