<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Optimal Dose Escalation Using Deep Reinforcement Learning</dc:title>
  <dc:title>R package RLescalation version 1.0.3</dc:title>
  <dc:description>An implementation to compute an optimal dose escalation rule
    using deep reinforcement learning in phase I oncology trials
    (Matsuura et al. (2023) &lt;doi:10.1080/10543406.2023.2170402&gt;).
    The dose escalation rule can directly optimize the percentages of correct
    selection (PCS) of the maximum tolerated dose (MTD).</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Imports: glue, R6, nleqslv, reticulate, stats, utils, zip</dc:relation>
  <dc:relation>Suggests: knitr, rmarkdown</dc:relation>
  <dc:creator>Kentaro Matsuura &lt;matsuurakentaro55@gmail.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Kentaro Matsuura [aut, cre, cph] (ORCID:
    &lt;https://orcid.org/0000-0001-5262-055X&gt;)</dc:contributor>
  <dc:rights>MIT + file LICENSE (https://CRAN.R-project.org/package=RLescalation/LICENSE)</dc:rights>
  <dc:date>2025-10-07</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=RLescalation</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.RLescalation</dc:identifier>
  <dc:language>en-US</dc:language>
</oai_dc:dc>
