<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Estimation of Ploidy and Detection of Aneuploidy Using
Genotyping Data</dc:title>
  <dc:title>R package Qploidy version 1.0.1</dc:title>
  <dc:description>Provides functions for estimating ploidy levels and detecting aneuploidy in individuals using 
             allele intensities or allele count data from high-throughput genotyping platforms, including 
             single nucleotide polymorphism (SNP) arrays and sequencing-based technologies. Implements an extended version of the 'PennCNV' 
             signal standardization method by Wang et al. (2007) &lt;doi:10.1101/gr.6861907&gt; for higher ploidy 
             levels. Computes B-allele frequencies (BAF), z-scores, and identifies copy number variation patterns.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 3.6.0)</dc:relation>
  <dc:relation>Imports: dplyr, ggplot2, tidyr, vroom, ggpubr, multtest, vcfR, stringr</dc:relation>
  <dc:relation>Suggests: covr, spelling, updog, rmdformats, knitr (&gt;= 1.10),
rmarkdown, testthat (&gt;= 3.0.0)</dc:relation>
  <dc:creator>Cristiane Taniguti &lt;cht47@cornell.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Cristiane Taniguti [cre, aut],
  Jeekin Lau [ctb],
  David Byrne [ctb],
  Oscar Riera-Lizarazu [ctb]</dc:contributor>
  <dc:rights>AGPL (&gt;= 3)</dc:rights>
  <dc:date>2025-05-01</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=Qploidy</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.Qploidy</dc:identifier>
  <dc:language>en-US</dc:language>
</oai_dc:dc>
