Tumor Mutation Detection in Plasma R package PlasmaMutationDetector version 1.7.2 Aims at detecting single nucleotide variation (SNV) and insertion/deletion (INDEL) in circulating tumor DNA (ctDNA), used as a surrogate marker for tumor, at each base position of an Next Generation Sequencing (NGS) analysis. Mutations are assessed by comparing the minor-allele frequency at each position to the measured PER in control samples. Software Depends: R (>= 3.4.0), ggplot2 (>= 2.2.0), grid (>= 3.4.0), GenomicRanges (>= 1.30.0), VariantAnnotation (>= 1.24.0) Imports: S4Vectors (>= 0.16.0), Rsamtools (>= 1.30.0), rtracklayer (>= 1.38.0), robustbase (>= 0.92-8), SummarizedExperiment (>= 1.8.0) Yves Rozenholc <yves.rozenholc@parisdescartes.fr> Comprehensive R Archive Network (CRAN) Yves Rozenholc, Nicolas Pécuchet, Pierre Laurent-Puig MIT + file LICENSE (https://CRAN.R-project.org/package=PlasmaMutationDetector/LICENSE) 2018-06-11 application/tgz https://CRAN.R-project.org/package=PlasmaMutationDetector doi:10.32614/CRAN.package.PlasmaMutationDetector