<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Phylogeny-Guided OTU-Specific Association Test for Microbiome
Data</dc:title>
  <dc:title>R package POSTm version 1.4</dc:title>
  <dc:description>Implements the Phylogeny-Guided Microbiome OTU-Specific Association 
    Test method, which boosts the testing power by adaptively borrowing 
    information from phylogenetically close OTUs (operational taxonomic units)
    of the target OTU. This method
    is built on a kernel machine regression framework and allows for flexible 
    modeling of complex microbiome effects, adjustments for covariates, and 
    can accommodate both continuous and binary outcomes. </dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: methods</dc:relation>
  <dc:relation>Imports: CompQuadForm, ape</dc:relation>
  <dc:relation>Suggests: multtest, rmarkdown, knitr</dc:relation>
  <dc:creator>Shannon T. Holloway &lt;shannon.t.holloway@gmail.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Caizhi Huang [aut],
  Jung-Ying Tzeng [aut],
  Shannon T. Holloway [aut, cre]</dc:contributor>
  <dc:rights>GPL-2</dc:rights>
  <dc:date>2024-04-17</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=POSTm</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.POSTm</dc:identifier>
</oai_dc:dc>
