<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Principal Component BiSulfite</dc:title>
  <dc:title>R package PCBS version 0.1.1</dc:title>
  <dc:description>A system for fast, accurate, and flexible whole genome bisulfite sequencing (WGBS) data analysis of two-condition comparisons. Principal Component BiSulfite, 'PCBS', assigns methylated loci eigenvector values from the treatment-delineating principal component in lieu of running millions of pairwise statistical tests, which dramatically increases analysis flexibility and reduces computational requirements. Methods: &lt;https://katlande.github.io/PCBS/articles/Differential_Methylation.html&gt;. </dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 2.10)</dc:relation>
  <dc:relation>Imports: ggplot2, tibble, ggrepel, dplyr, data.table</dc:relation>
  <dc:creator>Kathryn Lande &lt;kathryn.lande@mail.mcgill.ca&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Kathryn Lande [aut, cre, cph]</dc:contributor>
  <dc:rights>GPL-3</dc:rights>
  <dc:date>2024-08-27</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=PCBS</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.PCBS</dc:identifier>
</oai_dc:dc>