<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Optimal Two-Stage Designs for Ordered Categorical Outcomes</dc:title>
  <dc:title>R package OptOTrials version 1.0.2</dc:title>
  <dc:description>Functions to design and simulate optimal two-stage randomized
    controlled trials (RCTs) with ordered categorical outcomes, supporting
    rank-based tests and group-sequential decision rules. Methods build on
    classical and modern rank tests and two-stage/Group-Sequential designs,
    e.g., Park (2025) &lt;doi: 10.1371/journal.pone.0318211&gt;.  Please see the package reference
    manual and vignettes for details. </dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 4.0)</dc:relation>
  <dc:relation>Imports: stats</dc:relation>
  <dc:creator>Yeonhee Park &lt;yeonheepark@skku.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Yeonhee Park [aut, cre],
  Yudi Wang [aut],
  Zhanpeng Xu [aut]</dc:contributor>
  <dc:rights>GPL-3</dc:rights>
  <dc:date>2025-09-05</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=OptOTrials</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.OptOTrials</dc:identifier>
</oai_dc:dc>
