Design and Monitoring of Clinical Trials with Negative Binomial Endpoint R package NBDesign version 2.0.0 Calculate various functions needed for design and monitoring clinical trials with negative binomial endpoint with variable follow-up. This version has a few changes compared to the previous version 1.0.0, including (1) correct a typo in Type 1 censoring, mtbnull=bnull and (2) restructure the code to account for shape parameter equal to zero, i.e. Poisson scenario. Software Depends: R (>= 3.1.2) Imports: stats,PWEALL,MASS Xiaodong Luo <Xiaodong.Luo@sanofi.com> Comprehensive R Archive Network (CRAN) Xiaodong Luo [aut, cre], Sanofi [cph] GPL (>= 2) 2020-09-10 application/tgz https://CRAN.R-project.org/package=NBDesign doi:10.32614/CRAN.package.NBDesign