Microbiome Time-Series Data Analysis R package MicrobTiSDA version 0.1.0 Provides tools specifically designed for analyzing longitudinal microbiome data. This tool integrates seven functional modules, providing a systematic framework for microbiome time-series analysis. For more details on inferences involving interspecies interactions see Fisher (2014) <doi:10.1371/journal.pone.0102451>. Details on this package are also described in an unpublished manuscript. Software Depends: R (>= 3.5) Imports: caret, cluster, dplyr, ggdendro, ggplot2, ggraph, MASS, mgcv, plyr, pracma, randomForest, reshape2, scales, splines, stats, tibble, tidygraph, tidyr, vegan, visNetwork Suggests: knitr, rmarkdown, testthat (>= 3.0.0) Shijia Li <s.li2@uva.nl> Comprehensive R Archive Network (CRAN) Shijia Li [aut, cre] (ORCID: <https://orcid.org/0009-0006-6827-5344>) MIT + file LICENSE (https://CRAN.R-project.org/package=MicrobTiSDA/LICENSE) 2025-09-22 application/tgz https://CRAN.R-project.org/package=MicrobTiSDA doi:10.32614/CRAN.package.MicrobTiSDA