Generalized Spline Mixed Effect Models for Longitudinal Breath Data R package LoBrA version 1.0 Automated analysis and modeling of longitudinal 'omics' data (e.g. breath 'metabolomics') using generalized spline mixed effect models. Including automated filtering of noise parameters and determination of breakpoints. Software Depends: R (>= 3.5.0) Imports: methods, lawstat, nlme, graphics, RColorBrewer, stats, base, grDevices, qpdf Suggests: knitr, rmarkdown Anne-Christin Hauschild <achauschild@googlemail.com> Comprehensive R Archive Network (CRAN) Anne-Christin Hauschild [aut, cre] (ORCID: <https://orcid.org/0000-0002-7499-4373>), Sandy P. Eckel [ths, com], Jan Baumbach [ths] GPL-3 2022-03-21 application/tgz https://CRAN.R-project.org/package=LoBrA doi:10.32614/CRAN.package.LoBrA