<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>LUCID with Multiple Omics Data</dc:title>
  <dc:title>R package LUCIDus version 3.1.0</dc:title>
  <dc:subject>CRAN Task View: MissingData (https://CRAN.R-project.org/view=MissingData)</dc:subject>
  <dc:subject>CRAN Task View: Omics (https://CRAN.R-project.org/view=Omics)</dc:subject>
  <dc:description>Implements Latent Unknown Clusters By Integrating Multi-omics Data
    (LUCID; Peng (2019) &lt;doi:10.1093/bioinformatics/btz667&gt;) for integrative
    clustering with exposures, multi-omics data, and health outcomes.
    Supports three integration strategies: early, parallel, and serial.
    Provides model fitting and tuning, lasso-type regularization for exposure
    and omics feature selection, handling of missing data, including both
    sporadic and complete-case patterns, prediction, and g-computation for
    estimating causal effects of exposures, bootstrap inference for
    uncertainty estimation, and S3 summary and plot methods. For the
    multi-omics integration framework, see Jia (2024)
    &lt;https://journal.r-project.org/articles/RJ-2024-012/RJ-2024-012.pdf&gt;.
    For the missing-data imputation mechanism, see Jia (2024)
    &lt;doi:10.1093/bioadv/vbae123&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 3.6.0)</dc:relation>
  <dc:relation>Imports: mclust, nnet, boot, jsonlite, networkD3, progress, stats,
utils, glasso, glmnet</dc:relation>
  <dc:relation>Suggests: testthat (&gt;= 3.0.0)</dc:relation>
  <dc:creator>Qiran Jia &lt;qiranjia@usc.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Qiran Jia [aut, cre] (ORCID: &lt;https://orcid.org/0000-0002-0790-5967&gt;),
  Yinqi Zhao [aut] (ORCID: &lt;https://orcid.org/0000-0003-2413-732X&gt;),
  David Conti [ths] (ORCID: &lt;https://orcid.org/0000-0002-2941-7833&gt;),
  Jesse Goodrich [ctb] (ORCID: &lt;https://orcid.org/0000-0001-6615-0472&gt;)</dc:contributor>
  <dc:rights>MIT + file LICENSE (https://CRAN.R-project.org/package=LUCIDus/LICENSE)</dc:rights>
  <dc:date>2026-03-11</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=LUCIDus</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.LUCIDus</dc:identifier>
</oai_dc:dc>
