Implementation of LT-FH++ R package LTFHPlus version 2.2.0 Implementation of LT-FH++, an extension of the liability threshold family history (LT-FH) model. LT-FH++ uses a Gibbs sampler for sampling from the truncated multivariate normal distribution and allows for flexible family structures. LT-FH++ was first described in Pedersen, Emil M., et al. (2022) <doi:10.1016/j.ajhg.2022.01.009> as an extension to LT-FH with more flexible family structures, and again as the age-dependent liability threshold (ADuLT) model Pedersen, Emil M., et al. (2023) <https://www.nature.com/articles/s41467-023-41210-z> as an alternative to traditional time-to-event genome-wide association studies, where family history was not considered. Software Imports: batchmeans, dplyr, future.apply, future, purrr, Rcpp, rlang, stats, stringr, tibble, tmvtnorm, tidyselect, igraph, xgboost, tidyr, ggplot2 LinkingTo: Rcpp Suggests: MASS, knitr, rmarkdown, kinship2, testthat Emil Michael Pedersen <emp@ph.au.dk> Comprehensive R Archive Network (CRAN) Emil Michael Pedersen [aut, cre], Florian Privé [aut, ths], Bjarni Jóhann Vilhjálmsson [ths], Esben Agerbo [ths], Jette Steinbach [aut], Lucas Rasmussen [ctb] GPL-3 2025-11-17 application/tgz https://CRAN.R-project.org/package=LTFHPlus doi:10.32614/CRAN.package.LTFHPlus en-GB