Hybrid Design for Phase I Dose-Finding Studies R package HybridDesign version 1.0 The Hybrid design is a combination of model-assisted design (e.g., the modified Toxicity Probability Interval design) with dose-toxicity model-based design for phase I dose-finding studies. The hybrid design controls the overdosing toxicity well and leads to a recommended dose closer to the true maximum tolerated dose (MTD) due to its ability to calibrate for an intermediate dose. More details can be found in Liao et al. 2022 <doi:10.1002/ijc.34203>. Software Depends: R (>= 3.6) Imports: testit, ResourceSelection Heng Zhou <heng.zhou@merck.com> Comprehensive R Archive Network (CRAN) Heng Zhou [aut, cre], Feng Zhou [aut], Jason Liao [aut] GPL-3 2022-12-15 application/tgz https://CRAN.R-project.org/package=HybridDesign doi:10.32614/CRAN.package.HybridDesign