A User-Friendly R 'shiny' Application for Multi-Omics Data Integration and Analysis R package Holomics version 1.2.1 A 'shiny' application, which allows you to perform single- and multi-omics analyses using your own omics datasets. After the upload of the omics datasets and a metadata file, single-omics is performed for feature selection and dataset reduction. These datasets are used for pairwise- and multi-omics analyses, where automatic tuning is done to identify correlations between the datasets - the end goal of the recommended 'Holomics' workflow. Methods used in the package were implemented in the package 'mixomics' by Florian Rohart,Benoît Gautier,Amrit Singh,Kim-Anh Lê Cao (2017) <doi:10.1371/journal.pcbi.1005752> and are described there in further detail. Software Depends: R (>= 4.0) Imports: bs4Dash (>= 2.0.2), config, dplyr, DT, ggplot2, golem, igraph, openxlsx, readxl, shiny (>= 1.6.0), shinyalert, shinybusy, shinyjs, shinyvalidate, shinyWidgets, stringr, tippy, visNetwork, mixOmics, BiocParallel Suggests: bookdown, knitr, rmarkdown, badger Katharina Munk <katharinamunk@yahoo.de> Comprehensive R Archive Network (CRAN) Katharina Munk [aut, cre], Eva M. Molin [aut, ctb], Günter Brader [ctb], Lisa Ziemba [ctb], AIT Austrian Institute of Technology GmbH [cph] GPL (>= 3) 2025-11-15 application/tgz https://CRAN.R-project.org/package=Holomics doi:10.32614/CRAN.package.Holomics en-US