Toolkit for HLA Immunogenomics R package HLAtools version 1.6.3 A toolkit for the analysis and management of data for genes in the so-called "Human Leukocyte Antigen" (HLA) region. Functions extract reference data from the Anthony Nolan HLA Informatics Group/ImmunoGeneTics HLA 'GitHub' repository (ANHIG/IMGTHLA) <https://github.com/ANHIG/IMGTHLA>, validate Genotype List (GL) Strings, convert between UNIFORMAT and GL String Code (GLSC) formats, translate HLA alleles and GLSCs across ImmunoPolymorphism Database (IPD) IMGT/HLA Database release versions, identify differences between pairs of alleles at a locus, generate customized, multi-position sequence alignments, trim and convert allele-names across nomenclature epochs, and extend existing data-analysis methods. Software Depends: R (>= 3.6.0) Imports: DescTools, dplyr, fmsb, rvest, stats, stringr, tibble, utils, xfun Suggests: knitr, rmarkdown, testthat (>= 3.0.0) Steven Mack <Steven.Mack@ucsf.edu> Comprehensive R Archive Network (CRAN) Livia Tran [aut], Ryan Nickens [aut], Leamon Crooms IV [aut], Derek Pappas [aut], Vinh Luu [ctb], Josh Bredeweg [ctb], Steven Mack [aut, cre] (ORCID: <https://orcid.org/0000-0001-9820-9547>) GPL (>= 3) 2025-07-21 application/tgz https://CRAN.R-project.org/package=HLAtools doi:10.32614/CRAN.package.HLAtools