<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Group Sequential Design for Historical Control Trial with
Survival Outcome</dc:title>
  <dc:title>R package HCTDesign version 0.7.4</dc:title>
  <dc:description>It provides functions to design historical controlled trials with survival outcome by group sequential method. The options for interim look boundaries are efficacy only, efficacy &amp; futility or futility only. It also provides the function to monitor the trial for any unplanned look. The package is based on Jianrong Wu, Xiaoping Xiong (2016) &lt;doi:10.1002/pst.1756&gt; and Jianrong Wu, Yimei Li (2020) &lt;doi:10.1080/10543406.2019.1684305&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Imports: Rdpack, diversitree, mvtnorm, flexsurv, stats, survival,
crayon</dc:relation>
  <dc:creator>Tushar Patni &lt;tushar.patni006@gmail.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Tushar Patni [aut, cre],
  Yimei Li [aut],
  Jianrong Wu [aut]</dc:contributor>
  <dc:rights>GPL-3</dc:rights>
  <dc:date>2025-10-20</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=HCTDesign</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.HCTDesign</dc:identifier>
</oai_dc:dc>
