Generalized Two Arms Clinical Trial Sample Size Calculation R package GenTwoArmsTrialSize version 0.0.5 Two arms clinical trials required sample size is calculated in the comprehensive parametric context. The calculation is based on the type of endpoints(continuous/binary/time-to-event/ordinal), design (parallel/crossover), hypothesis tests (equality/noninferiority/superiority/equivalence), trial arms noncompliance rates and expected loss of follow-up. Methods are described in: Chow SC, Shao J, Wang H, Lokhnygina Y (2017) <doi:10.1201/9781315183084>, Wittes, J (2002) <doi:10.1093/epirev/24.1.39>, Sato, T (2000) <doi:10.1002/1097-0258(20001015)19:19%3C2689::aid-sim555%3E3.0.co;2-0>, Lachin J M, Foulkes, M A (1986) <doi:10.2307/2531201>, Whitehead J(1993) <doi:10.1002/sim.4780122404>, Julious SA (2023) <doi:10.1201/9780429503658>. Software Imports: TrialSize, dplyr, Hmisc Suggests: knitr, rmarkdown Chel Hee Lee <chelhee.lee@ucalgary.ca> Comprehensive R Archive Network (CRAN) Mohsen Soltanifar [aut] (ORCID: <https://orcid.org/0000-0002-5989-0082>), Chel Hee Lee [cre, aut] (ORCID: <https://orcid.org/0000-0001-8209-8176>) GPL-3 2024-03-16 application/tgz https://CRAN.R-project.org/package=GenTwoArmsTrialSize doi:10.32614/CRAN.package.GenTwoArmsTrialSize