Genotype-Specific Survival Estimation R package GSSE version 0.1 CRAN Task View: Survival (https://CRAN.R-project.org/view=Survival) We propose a fully efficient sieve maximum likelihood method to estimate genotype-specific distribution of time-to-event outcomes under a nonparametric model. We can handle missing genotypes in pedigrees. We estimate the time-dependent hazard ratio between two genetic mutation groups using B-splines, while applying nonparametric maximum likelihood estimation to the reference baseline hazard function. The estimators are calculated via an expectation-maximization algorithm. Software Depends: R(>= 3.0.1) Imports: Iso (>= 0.0-17), splines, stats, zoo (>= 1.7-12) Suggests: MASS Baosheng Liang <liangbsunc@gmail.com> Comprehensive R Archive Network (CRAN) Baosheng Liang, Yuanjia Wang and Donglin Zeng GPL (>= 2) 2015-10-20 application/tgz https://CRAN.R-project.org/package=GSSE doi:10.32614/CRAN.package.GSSE