<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Estimation of Cell Infiltration Based on Cell Crosstalk</dc:title>
  <dc:title>R package CITMIC version 0.1.3</dc:title>
  <dc:description>A systematic biology tool was developed to identify cell infiltration via Individualized Cell-Cell interaction network. 'CITMIC' first constructed a weighted cell interaction network through integrating Cell-target interaction information, molecular function data from Gene Ontology (GO) database and gene transcriptomic data in specific sample, and then, it used a network propagation algorithm on the network to identify cell infiltration for the sample. Ultimately, cell infiltration in the patient dataset was obtained by normalizing the centrality scores of the cells.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 2.10)</dc:relation>
  <dc:relation>Imports: fastmatch, igraph, parallel, stats</dc:relation>
  <dc:relation>Suggests: knitr, rmarkdown</dc:relation>
  <dc:creator>Junwei Han &lt;hanjunwei1981@163.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Junwei Han [aut, cre, cph],
  Xilong Zhao [aut]</dc:contributor>
  <dc:rights>GPL (&gt;= 2)</dc:rights>
  <dc:date>2025-10-15</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=CITMIC</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.CITMIC</dc:identifier>
</oai_dc:dc>