Generalized Pairwise Comparisons R package BuyseTest version 3.3.9 CRAN Task View: CausalInference (https://CRAN.R-project.org/view=CausalInference) Implementation of the Generalized Pairwise Comparisons (GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for complete observations, and extended in Peron (2018) <doi:10.1177/0962280216658320> to deal with right-censoring. GPC compare two groups of observations (intervention vs. control group) regarding several prioritized endpoints to estimate the probability that a random observation drawn from one group performs better/worse/equivalently than a random observation drawn from the other group. Summary statistics such as the net treatment benefit, win ratio, or win odds are then deduced from these probabilities. Confidence intervals and p-values are obtained based on asymptotic results (Ozenne 2021 <doi:10.1177/09622802211037067>), non-parametric bootstrap, or permutations. The software enables the use of thresholds of minimal importance difference, stratification, non-prioritized endpoints (O Brien test), and can handle right-censoring and competing-risks. Software Depends: R (>= 3.5.0), Rcpp Imports: data.table, doSNOW, foreach, ggplot2, methods, lava, parallel, prodlim, riskRegression, rlang, scales, stats, stats4, utils LinkingTo: Rcpp, RcppArmadillo Suggests: cvAUC, mvtnorm, pbapply, pROC, R.rsp, survival, testthat Brice Ozenne <brice.mh.ozenne@gmail.com> Comprehensive R Archive Network (CRAN) Brice Ozenne [aut, cre] (ORCID: <https://orcid.org/0000-0001-9694-2956>), Eva Cantagallo [aut], William Anderson [aut], Julien Peron [ctb], Johan Verbeeck [ctb] GPL-3 2026-06-01 application/tgz https://CRAN.R-project.org/package=BuyseTest doi:10.32614/CRAN.package.BuyseTest