Adaptive Subgroup Selection in Group Sequential Trials R package ASSISTant version 1.4.3 CRAN Task View: ClinicalTrials (https://CRAN.R-project.org/view=ClinicalTrials) Clinical trial design for subgroup selection in three-stage group sequential trial as described in Lai, Lavori and Liao (2014, <doi:10.1016/j.cct.2014.09.001>). Includes facilities for design, exploration and analysis of such trials. An implementation of the initial DEFUSE-3 trial is also provided as a vignette. Software Imports: R6, mvtnorm, knitr, magrittr, dplyr Suggests: rmarkdown Balasubramanian Narasimhan <naras@stat.Stanford.EDU> Comprehensive R Archive Network (CRAN) Tze Leung Lai [ctb], Philip Lavori [aut], Olivia Liao [aut], Balasubramanian Narasimhan [aut, cre], Ka Wai Tsang [aut] GPL (>= 2) 2022-12-02 application/tgz https://CRAN.R-project.org/package=ASSISTant doi:10.32614/CRAN.package.ASSISTant