Package: POSTm
Type: Package
Title: Phylogeny-Guided OTU-Specific Association Test for Microbiome
        Data
Version: 1.4
Date: 2024-04-17
Authors@R: c(person("Caizhi", "Huang", role = "aut"),
             person("Jung-Ying", "Tzeng", role = "aut"),
             person("Shannon T.", "Holloway", role = c("aut", "cre"),
                     email = "shannon.t.holloway@gmail.com"))
Author: Caizhi Huang [aut],
  Jung-Ying Tzeng [aut],
  Shannon T. Holloway [aut, cre]
Maintainer: Shannon T. Holloway <shannon.t.holloway@gmail.com>
Description: Implements the Phylogeny-Guided Microbiome OTU-Specific Association 
    Test method, which boosts the testing power by adaptively borrowing 
    information from phylogenetically close OTUs (operational taxonomic units)
    of the target OTU. This method
    is built on a kernel machine regression framework and allows for flexible 
    modeling of complex microbiome effects, adjustments for covariates, and 
    can accommodate both continuous and binary outcomes. 
Depends: methods
Imports: CompQuadForm, ape
Suggests: multtest, rmarkdown, knitr
biocViews:
License: GPL-2
Encoding: UTF-8
LazyData: true
VignetteBuilder: knitr
RoxygenNote: 7.3.1
Collate: 'ACAT.R' 'CKAT.R' 'POSTmData.R' 'distanceMatrix.R'
        'getKernel.R' 'glmFit.R' 'lmFit.R' 'p.adjust.POST.R'
        'plot.POST.R' 'post.R' 'print.POST.R'
NeedsCompilation: no
Packaged: 2024-04-17 22:52:04 UTC; 19194
Repository: CRAN
Date/Publication: 2024-04-17 23:10:18 UTC
Built: R 4.4.3; ; 2026-03-23 03:30:24 UTC; windows
